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CD28 Human

CD28 Human

Description: Recombinant Human CD28
Source: E.coli
Order No.: C65618-0002
Size: 2μg
Price:595.00
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Synonyms
T-cell-specific surface glycoprotein CD28, TP44, CD_antigen: CD28, T-cell-specific surface glycoprotein CD28 isoform 1.



Introduction
CD28 co-stimulation is necessary for CD4 positive T-cell proliferation & survival, interleukin-2 production, and T-helper type-2 development. Human post-thymic regulatory T cells require CD28 co-stimulation to expand and maintain potent suppressive function in vivo. Apoptosis plays a key role in the age-related decline of CD28 expression and in immunosenescence.



Description
CD28 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 376 amino acids (19-152a.a.) and having a molecular mass of 42.4kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). CD28 is expressed with a 242 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.



Source
Sf9, Baculovirus cells.



Purity
Greater than 90.0% as determined by SDS-PAGE.

Product Datasheets

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