cGMP Recombinant Human Vascular Endothelial Growth Factor, rHu VEGF

Recombinant Human Vascular Endothelial Growth Factor-A is expressed at high levels in certain tumor-derived cells but is produced by a wide variety of cell types.

Features and Specifications
Custom packaging and sizes available
Single-use syringe configuration
Lyophilized or liquid format
Pharmaceutical grade
Sterile-filled
Custom biological activity assays available


In contrast to other factors mitogenic for endothelial cells such as FGF-1, FGF-2 and PDGF, VEGF is synthesized as a precursor containing a typical hydrophobic secretory signal sequence of 26 amino acids. Glycosylation is not required for efficient secretion of VEGF. rHu VEGF-121 produced in E. coli is a double, non-glycosylated, polypeptide chain that contains 121 amino acids and has a molecular mass of 28.42 kDa. rHu Vascular Endothelial Growth Factor expressed in CHO cells is a double, glycosylated, polypeptide chain containing full length VEGF containing 165 amino acids (VEGF-165).