PODS® Human BMP-4

PODS® co-crystals	PODS® co-crystals

PODS 技术

将生长因子包埋进蛋白质晶体（多角体蛋白）中，多角体蛋白能够保护包埋的生长因子，并维持其稳定性与生物活性，进而持续释放到细胞培养系统中。

PODS BMP-4 描述

BMP (Bone morphogenetic protein,人骨形态发生蛋白) 是1963年美国的Marshall R.Urist教授发现的。骨形态发生蛋白能够诱导动物或人体间充质细胞分化为骨、软骨、韧带、肌腱和神经组织。

The product contains the polyhedrin protein co-crystalized with Human BMP-4. Bone Morphogenic Protein 4 (BMP-4) is a member of the Bone Morphogenetic Protein (BMP) family. These proteins are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. BMP proteinsstimulate the production of bone matrix proteins and osteoclasts proliferation, and can be found on tissues related with bone or cartilage growth.

PODS BMP-4 文件资料

PPH56 Datasheet

PODS User Guide

PODS MSDS

相关文章

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PODS BMP-4 规格

PODS GDNF 使用建议

PODS® co-crystals provide a depot of proteins which are steadily secreted. It has been estimated that the biological activity of 50 million PODS® co-crystals generates the same peak dose as 3.3 μg of standard recombinant protein. However, at 5 days following the start of seeding the PODS® co-crystals, there are more than 50% of these peak levels still present in the culture system. Ultimately, the amount of PODS® co-crystals that is optimal for a particular experiment should be determined empirically. Based on previous data, we suggest using 50 million PODS® co-crystals in place of 3.3 μg of standard growth factor as a starting point."

To control for cross-reactivity with cells or as a negative control, we recommend using PODS® growth factors alongside PODS® Empty crystals, as the latter do not contain or release cargo protein.

PODS BMP-4 AA Sequence

MADVAGTSNR DFRGREQRLF NSEQYNYNNS KNSRPSTSLY KKAGSIPGNR MLMVVLLCQV LLGGASHASL IPETGKKKVA EIQGHAGGRR SGQSHELLRD FEATLLQMFG LRRRPQPSKS AVIPDYMRDL YRLQSGEEEE EQIHSTGLEY PERPASRANT VRSFHHEEHL ENIPGTSENS AFRFLFNLSS IPENEAISSA ELRLFREQVD QGPDWERGFH RINIYEVMKP PAEVVPGHLI TRLLDTRLVH HNVTRWETFD VSPAVLRWTR EKQPNYGLAI EVTHLHQTRT HQGQHVRISR SLPQGSGNWA QLRPLLVTFG HDGRGHALTR RRRAKRSPKH HSQRARKKNK NCRRHSLYVD FSDVGWNDWI VAPPGYQAFY CHGDCPFPLA DHLNSTNHAI VQTLVNSVNS SIPKACCVPT ELSAISMLYL DEYDKVVLKN YQEMVVEGCG CR

PODS BMP-4 Alternative Names

Bone morphogenetic protein 4, bone morphogenetic protein 4A, BMP-4A, BMP4, BMP4A,  人骨形态发生蛋白4